منابع مشابه
Genetic factors for obesity.
The purpose of the present study was to identify gene polymorphisms for the reliable assessment of genetic factors for obesity. The study population comprised 3906 unrelated Japanese individuals (2286 men, 1620 women), including 1196 subjects (677 men, 519 women) with obesity (body mass index of > or = 25 kg/m2) and 2710 controls (1609 men, 1101 women). The genotypes for 147 polymorphisms of 12...
متن کاملGenetic factors in human obesity.
The recent increase in the prevalence of obesity in many parts of the world is clearly driven by secular changes in exposure to environmental factors, including the increased availability and reduced costs of energy-den e food and a reduction in physical activity during work and lei ure time (1,2). The peed with which this 'obesity epidemic' has occurred has led to the widespread misconception ...
متن کاملObesity in childhood and adolescence, genetic factors.
Obesity and overweight are a pandemic phenomenon in the modern world. Childhood and adolescent obesity often ends up in obesity in adults. The costs of obesity and its consequences are staggering for any society, crippling for countries in development. The etiology is complex, but most often idiopathic. Hormonal, syndromic and medication-induced obesity are well investigated. Genetic causes are...
متن کاملGenetic factors associated with susceptibility to obesity
This review discusses the various genetic factors and gene products (proteins) related to obesity. The three fundamental mechanisms underlying obesity are: relative increase in energy intake; reLative decrease in energy expenditure; and preferential partitioning of ingested calories to fat storage. Gene defects can be related to any one of these mechanisms, either alone or together. Many geneti...
متن کاملShared genetic risk factors for obstructive sleep apnea and obesity.
Both obesity and obstructive sleep apnea (OSA) are complex disorders with multiple risk factors, which interact in a complicated fashion to determine the overall phenotype. In addition to environmental risk factors, each disorder has a strong genetic basis that is likely due to the summation of small to moderate effects from a large number of genetic loci. Obesity is a strong risk factor for sl...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2006
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.18.5.843